“Most Lynch syndrome mutation carriers aren't aware of it because genetic testing rates and knowledge about the condition are much lower than for other cancer-predisposing genes like BRCA1 and BRCA2, which are associated with breast and ovarian cancer,” said Sapna Syngal, MD, MPH, Director of Research at the Center for Cancer Genetics and Prevention in the Population Sciences Division at Dana-Farber, and senior author of the report. The new online model, developed by Dana-Farber researchers and doctors, is called PREMM5, and enables people to quickly assess their likelihood of carrying one of these genes associated with Lynch syndrome ( J Clin Oncol 2017 doi:10.1200/JCO.20). The five genes are MLH1, MSH2, MSH6, PMS2, and EPCAM. Mutations in these so-called “mismatch repair” genes impair cells' ability to heal breaks in their DNA, making genetically damaged cells prone to abnormal growth and the development of cancer. SimpleSYN also offers the ideal platform for sales representatives or individuals for a fast Outlook synchronization between various computers.An online assessment tool developed at Dana-Farber Cancer Institute, Boston, can help rapidly identify people who should undergo genetic testing for Lynch syndrome, an inherited disorder that greatly increases the lifetime risk of colorectal, endometrial, ovarian, stomach, and other cancers.Īn estimated 1 in 279 individuals-nearly a million people in the U.S.-carry a mutation in one of five different genes that can cause Lynch syndrome. With SimpleSYN you can use Outlook together as a team, e.g., to run a common calendar to keep their schedule current, or to provide a central databank for contacts.
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SimpleSYN is the ideal software for work teams and companies who must frequently exchange Outlook data. SimpleSYN can deliver! You can configure SimpleSYN individually on multiple computers so that your colleague receives the newest appointments and tasks, but not the e-mails irrelevant to his work. You would like to synchronize different Outlook folders on several computers? This way you can synchronize changes to the Outlook database in one direction only or just synchronize new and altered e-mails. Direction and type of synchronization (new, altered and deleted elements) can be individually configured for every Outlook folder. SimpleSYN is completely flexible in its setup.
The clear and intuitive user interface allows new users to easily navigate through the program. After the initial synchronization the program initiates the data exchange automatically as soon as an Outlook element is changed on a computer. Only a few simple steps and the practical Sync-software is installed, ready to use, and running unobtrusively in the background. The data synchronization is carried out via network or, in the business version, optionally over the Internet automatically and in real-time! Whether you wish to synchronize e-mails, appointments, contacts, notes or tasks, SimpleSYN will keep your data up-to-date and uniform, regardless of where you are. SimpleSYN is the synchronization solution for synchronizing Outlook on several computers effectively and competitively.
The data synchronization is carried out via network or, in the business version, optionally over the Internet SimpleSYN Screenshot Version: 3
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